What Studies Show about the CalmPro Formula and Ingredients

“For dogs with territorial aggression, tryptophan supplementation of a low protein diet may be helpful in reducing aggression 1

“Five healthy Dogs were evaluated. From initial results of this study, it appears that at standard doses, the formula is a safe product with no immediate effects on blood or urine parameters. No significant abnormalities or changes were observed.” 2

“The same dogs were again evaluated before performing the same test as before. The product was administered at three times the label recommended dose daily for five consecutive days. At triple the recommended dose, the only changes observed were a slight reduction in the thrombocyte count in 4 out of the 5 dogs. The thrombocyte count returned to normal in the 4 abnormal dogs after 3 weeks.” 3

“13 dogs and 2 cats were to be tested on two separate occasions. Results are as follows: After the 1st dose, 12 of the 13 dogs and both of the cats tested had a mild degree of sedation. After the 2nd dose, 10 of the 13 dogs and 1 of the cats tested had a mild degree of sedation. 60% of the participating owners said that the formula did work for their pet.” 4



1 DeNapoli J.D., Dodman N.H., Shuster L., Rand W.M., Gross K.L., “Effect of dietary protein content and tryptophan supplementation on dominance aggression, territorial aggression, and hyperactivity in dogs.” Journal of the American Veterinary Medical Association. Vol. 217, No. 4, August 2000: 504-508.
2 John A. Mulnix, D.V.M., M.S. “Canine ProQuiet formula laboratory evaluation.” Ft. Collins, CO, November 1998.
3 John A. Mulnix, D.V.M., M.S. “Canine ProQuiet laboratory evaluation in five dogs - triple dose study.” Ft. Collins, CO, March 2000.
4 John A. Mulnix, D.V.M., M.S. “ProQuiet efficacy study.” Ft. Collins, CO, March 2000.